# Study of the Role of PCSK9 and FXR in the Physiopathology of the Joint Dyslipidemia Associated to the Human Immunoresistance

> **NCT00422006** · NA · COMPLETED · sponsor: **Nantes University Hospital** · enrollment: 111 (actual)

## Conditions studied

- Obesity

## Interventions

- **PROCEDURE:** biopsy of muscle, of liver, and of adipose tissue
- **PROCEDURE:** clamp euglycemic - hyperglycemic
- **BEHAVIORAL:** diet
- **OTHER:** biopsies for biological and genetic analyses

## Key facts

- **NCT ID:** NCT00422006
- **Lead sponsor:** Nantes University Hospital
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2008-02
- **Primary completion:** 2013-11
- **Final completion:** 2013-11
- **Target enrollment:** 111 (ACTUAL)
- **Last updated:** 2014-04-03


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00422006

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00422006, "Study of the Role of PCSK9 and FXR in the Physiopathology of the Joint Dyslipidemia Associated to the Human Immunoresistance". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT00422006. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*