# Study of an Investigational Drug for the Prevention of Thrombosis-related Events Following Hip Replacement Surgery (ADVANCE-3)

> **NCT00423319** · PHASE3 · COMPLETED · sponsor: **Bristol-Myers Squibb** · enrollment: 5407 (actual)

## Conditions studied

- Deep Vein Thrombosis
- Pulmonary Embolism

## Interventions

- **DRUG:** Enoxaparin
- **DRUG:** Apixaban
- **DRUG:** Enoxaparin-matching placebo
- **DRUG:** Apixaban-matching placebo

## Key facts

- **NCT ID:** NCT00423319
- **Lead sponsor:** Bristol-Myers Squibb
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2007-03
- **Primary completion:** 2009-09
- **Final completion:** 2009-09
- **Target enrollment:** 5407 (ACTUAL)
- **Last updated:** 2014-05-14


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00423319

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00423319, "Study of an Investigational Drug for the Prevention of Thrombosis-related Events Following Hip Replacement Surgery (ADVANCE-3)". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT00423319. Licensed CC0.

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