# Combination Therapy in Pulmonary Arterial Hypertension

> **NCT00433329** · PHASE4 · COMPLETED · sponsor: **Actelion** · enrollment: 100 (actual)

## Conditions studied

- Pulmonary Arterial Hypertension

## Interventions

- **DRUG:** Bosentan
- **DRUG:** Sildenafil

## Key facts

- **NCT ID:** NCT00433329
- **Lead sponsor:** Actelion
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2007-03
- **Primary completion:** 2010-05
- **Final completion:** 2010-08
- **Target enrollment:** 100 (ACTUAL)
- **Last updated:** 2025-02-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00433329

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00433329, "Combination Therapy in Pulmonary Arterial Hypertension". Retrieved via AI Analytics 2026-06-05 from https://api.ai-analytics.org/clinical/NCT00433329. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*