Combination Chemotherapy and Rituximab in Treating Patients With Untreated Mantle Cell Lymphoma

NCT00433537 · clinicaltrials.gov ↗

PHASE2

Phase

COMPLETED

Status

77

Enrollment

NIH

Sponsor class

Conditions

Contiguous Stage II Mantle Cell Lymphoma
Noncontiguous Stage II Mantle Cell Lymphoma
Stage I Mantle Cell Lymphoma
Stage III Mantle Cell Lymphoma
Stage IV Mantle Cell Lymphoma

Interventions

DRUG: bortezomib
BIOLOGICAL: rituximab
DRUG: cyclophosphamide
DRUG: doxorubicin hydrochloride
DRUG: vincristine
DRUG: dexamethasone
BIOLOGICAL: filgrastim
BIOLOGICAL: pegfilgrastim
PROCEDURE: Autologous stem cell transplantation (ASCT)

Sponsor

National Cancer Institute (NCI)