# Tumor Necrosis Factor in Patients Undergoing Surgery for Primary Cancer or Metastatic Cancer

> **NCT00436410** · EARLY_PHASE1 · COMPLETED · sponsor: **National Institutes of Health Clinical Center (CC)** · enrollment: 108 (estimated)

## Conditions studied

- Adrenocortical Carcinoma
- Breast Cancer
- Colorectal Cancer
- Gastrointestinal Cancer
- Kidney Cancer
- Liver Cancer
- Melanoma (Skin)
- Ovarian Cancer
- Pancreatic Cancer
- Sarcoma

## Interventions

- **BIOLOGICAL:** colloidal gold-bound tumor necrosis factor
- **OTHER:** electron microscopy
- **OTHER:** pharmacological study
- **PROCEDURE:** conventional surgery

## Key facts

- **NCT ID:** NCT00436410
- **Lead sponsor:** National Institutes of Health Clinical Center (CC)
- **Sponsor class:** NIH
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2006-12
- **Primary completion:** —
- **Final completion:** 2009-08
- **Target enrollment:** 108 (ESTIMATED)
- **Last updated:** 2012-05-02

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00436410

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00436410, "Tumor Necrosis Factor in Patients Undergoing Surgery for Primary Cancer or Metastatic Cancer". Retrieved via AI Analytics 2026-06-26 from https://api.ai-analytics.org/clinical/NCT00436410. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*