# Safety and Effectiveness Study of a Candidate Vaginal Microbicide for Prevention of HIV

> **NCT00441298** · PHASE2 · COMPLETED · sponsor: **Centre for the AIDS Programme of Research in South Africa** · enrollment: 889 (actual)

## Conditions studied

- HIV Infections

## Interventions

- **DRUG:** Tenofovir gel
- **DRUG:** Placebo (Universal HEC placebo)

## Key facts

- **NCT ID:** NCT00441298
- **Lead sponsor:** Centre for the AIDS Programme of Research in South Africa
- **Sponsor class:** NETWORK
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2007-05
- **Primary completion:** 2009-12
- **Final completion:** 2010-03
- **Target enrollment:** 889 (ACTUAL)
- **Last updated:** 2016-02-01

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00441298

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00441298, "Safety and Effectiveness Study of a Candidate Vaginal Microbicide for Prevention of HIV". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT00441298. Licensed CC0.

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