# Efficacy and Safety of Seroquel and Lithium as Monotherapy in Acute Mania Treatment in Bipolar Disorder Patients

> **NCT00448578** · PHASE3 · COMPLETED · sponsor: **AstraZeneca** · enrollment: 150 (—)

## Conditions studied

- Mania
- Bipolar Disorder

## Interventions

- **DRUG:** Quetiapine Fumarate
- **DRUG:** Lithium

## Key facts

- **NCT ID:** NCT00448578
- **Lead sponsor:** AstraZeneca
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2005-08
- **Primary completion:** —
- **Final completion:** 2006-06
- **Target enrollment:** 150 (—)
- **Last updated:** 2010-12-09


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00448578

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00448578, "Efficacy and Safety of Seroquel and Lithium as Monotherapy in Acute Mania Treatment in Bipolar Disorder Patients". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT00448578. Licensed CC0.

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