# VEGF Trap in Treating Patients With Recurrent Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery

> **NCT00450255** · PHASE2 · COMPLETED · sponsor: **National Cancer Institute (NCI)** · enrollment: 41 (actual)

## Conditions studied

- Ciliary Body and Choroid Melanoma, Medium/Large Size
- Extraocular Extension Melanoma
- Iris Melanoma
- Metastatic Intraocular Melanoma
- Recurrent Intraocular Melanoma
- Recurrent Melanoma
- Stage III Melanoma
- Stage IV Melanoma

## Interventions

- **BIOLOGICAL:** ziv-aflibercept
- **OTHER:** pharmacological study

## Key facts

- **NCT ID:** NCT00450255
- **Lead sponsor:** National Cancer Institute (NCI)
- **Sponsor class:** NIH
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2007-06
- **Primary completion:** 2011-01
- **Final completion:** 2011-01
- **Target enrollment:** 41 (ACTUAL)
- **Last updated:** 2018-05-24


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00450255

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00450255, "VEGF Trap in Treating Patients With Recurrent Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT00450255. Licensed CC0.

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