# Efficacy and Safety Study of HZT-501 in Reducing the Risk of Ibuprofen-associated Ulcers

> **NCT00450658** · PHASE3 · COMPLETED · sponsor: **Amgen** · enrollment: 627 (actual)

## Conditions studied

- Peptic Ulcer

## Interventions

- **DRUG:** HZT-501
- **DRUG:** Ibuprofen

## Key facts

- **NCT ID:** NCT00450658
- **Lead sponsor:** Amgen
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2007-03
- **Primary completion:** 2008-09
- **Final completion:** 2008-10
- **Target enrollment:** 627 (ACTUAL)
- **Last updated:** 2024-12-16


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00450658

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00450658, "Efficacy and Safety Study of HZT-501 in Reducing the Risk of Ibuprofen-associated Ulcers". Retrieved via AI Analytics 2026-06-30 from https://api.ai-analytics.org/clinical/NCT00450658. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*