# Study of an Investigational Drug for the Prevention of Thrombosis-related Events Following Knee Replacement Surgery

> **NCT00452530** · PHASE3 · COMPLETED · sponsor: **Bristol-Myers Squibb** · enrollment: 3221 (actual)

## Conditions studied

- Deep Vein Thrombosis
- Pulmonary Embolism

## Interventions

- **DRUG:** Enoxaparin
- **DRUG:** Apixaban
- **DRUG:** Enoxaparin-matching placebo
- **DRUG:** Apixaban-matching placebo

## Key facts

- **NCT ID:** NCT00452530
- **Lead sponsor:** Bristol-Myers Squibb
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2007-06
- **Primary completion:** 2009-01
- **Final completion:** 2009-01
- **Target enrollment:** 3221 (ACTUAL)
- **Last updated:** 2014-07-09


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00452530

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00452530, "Study of an Investigational Drug for the Prevention of Thrombosis-related Events Following Knee Replacement Surgery". Retrieved via AI Analytics 2026-08-17 from https://api.ai-analytics.org/clinical/NCT00452530. Licensed CC0.

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