# Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to the Brain

> **NCT00452868** · EARLY_PHASE1 · COMPLETED · sponsor: **Wake Forest University Health Sciences** · enrollment: 14 (actual)

## Conditions studied

- Brain and Central Nervous System Tumors
- Cognitive/Functional Effects
- Long-term Effects Secondary to Cancer Therapy in Children
- Neurotoxicity
- Psychosocial Effects of Cancer and Its Treatment
- Radiation Toxicity

## Interventions

- **DRUG:** Donepezil

## Key facts

- **NCT ID:** NCT00452868
- **Lead sponsor:** Wake Forest University Health Sciences
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2006-06
- **Primary completion:** 2010-02
- **Final completion:** 2010-02
- **Target enrollment:** 14 (ACTUAL)
- **Last updated:** 2018-09-07

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00452868

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00452868, "Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to the Brain". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT00452868. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*