# Study of the Safety and Effectiveness of DIAM™ Spinal Stabilization System Versus Conservative Care

> **NCT00456378** · NA · TERMINATED · sponsor: **Medtronic Spinal and Biologics** · enrollment: 311 (actual)

## Conditions studied

- Lumbar Degenerative Disc Disease

## Interventions

- **DEVICE:** DIAM™ Spinal Stabilization System
- **PROCEDURE:** Conservative care

## Key facts

- **NCT ID:** NCT00456378
- **Lead sponsor:** Medtronic Spinal and Biologics
- **Sponsor class:** INDUSTRY
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2006-12
- **Primary completion:** 2015-10-08
- **Final completion:** 2018-11-20
- **Target enrollment:** 311 (ACTUAL)
- **Why stopped:** Business decision, no safety concerns
- **Last updated:** 2018-12-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00456378

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00456378, "Study of the Safety and Effectiveness of DIAM™ Spinal Stabilization System Versus Conservative Care". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT00456378. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*