# Role of Endorphins in the Perception of Dyspnea in Patients With Chronic Obstructive Pulmonary Disease

> **NCT00458419** · NA · COMPLETED · sponsor: **Dartmouth-Hitchcock Medical Center** · enrollment: 17 (actual)

## Conditions studied

- Chronic Obstructive Pulmonary Disease

## Interventions

- **DRUG:** naloxone versus placebo
- **DRUG:** intravenous injection of normal saline or naloxone

## Key facts

- **NCT ID:** NCT00458419
- **Lead sponsor:** Dartmouth-Hitchcock Medical Center
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2005-09
- **Primary completion:** —
- **Final completion:** 2007-05
- **Target enrollment:** 17 (ACTUAL)
- **Last updated:** 2007-11-02


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00458419

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00458419, "Role of Endorphins in the Perception of Dyspnea in Patients With Chronic Obstructive Pulmonary Disease". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT00458419. Licensed CC0.

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