# Chemotherapy With or Without Imatinib and/or Peripheral Stem Cell Transplant in Acute Lymphoblastic Leukemia

> **NCT00458848** · PHASE2 · COMPLETED · sponsor: **Gruppo Italiano Malattie EMatologiche dell'Adulto** · enrollment: 470 (actual)

## Conditions studied

- Leukemia

## Interventions

- **DRUG:** asparaginase
- **DRUG:** daunorubicin hydrochloride
- **DRUG:** etoposide
- **DRUG:** idarubicin
- **DRUG:** imatinib mesylate
- **DRUG:** mercaptopurine
- **DRUG:** methotrexate
- **DRUG:** methylprednisolone
- **DRUG:** mitoxantrone hydrochloride
- **DRUG:** prednisone
- **DRUG:** vincristine sulfate
- **PROCEDURE:** allogeneic hematopoietic stem cell transplantation
- **PROCEDURE:** autologous hematopoietic stem cell transplantation
- **PROCEDURE:** peripheral blood stem cell transplantation
- **RADIATION:** radiation therapy

## Key facts

- **NCT ID:** NCT00458848
- **Lead sponsor:** Gruppo Italiano Malattie EMatologiche dell'Adulto
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2004-10
- **Primary completion:** 2014-03
- **Final completion:** 2014-03
- **Target enrollment:** 470 (ACTUAL)
- **Last updated:** 2019-02-15


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00458848

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00458848, "Chemotherapy With or Without Imatinib and/or Peripheral Stem Cell Transplant in Acute Lymphoblastic Leukemia". Retrieved via AI Analytics 2026-06-26 from https://api.ai-analytics.org/clinical/NCT00458848. Licensed CC0.

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