# Patent Foramen Ovale Closure or Medical Therapy After Stroke - RESPECT Trial

> **NCT00465270** · NA · COMPLETED · sponsor: **Abbott Medical Devices** · enrollment: 980 (actual)

## Conditions studied

- Cryptogenic Stroke

## Interventions

- **DEVICE:** AMPLATZER PFO Occluder
- **OTHER:** Standard of Care - Medical Management

## Key facts

- **NCT ID:** NCT00465270
- **Lead sponsor:** Abbott Medical Devices
- **Sponsor class:** INDUSTRY
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2003-08
- **Primary completion:** 2012-05
- **Final completion:** 2016-05
- **Target enrollment:** 980 (ACTUAL)
- **Last updated:** 2019-02-18


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00465270

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00465270, "Patent Foramen Ovale Closure or Medical Therapy After Stroke - RESPECT Trial". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT00465270. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*