# Combination Chemotherapy in Treating Young Patients With Recurrent or Resistant Malignant Germ Cell Tumors

> **NCT00467051** · PHASE2 · COMPLETED · sponsor: **Children's Oncology Group** · enrollment: 20 (actual)

## Conditions studied

- Childhood Extracranial Germ Cell Tumor
- Childhood Extragonadal Malignant Germ Cell Tumor
- Childhood Malignant Ovarian Germ Cell Tumor
- Childhood Malignant Testicular Germ Cell Tumor
- Ovarian Choriocarcinoma
- Ovarian Embryonal Carcinoma
- Ovarian Yolk Sac Tumor
- Recurrent Childhood Malignant Germ Cell Tumor
- Recurrent Malignant Testicular Germ Cell Tumor
- Recurrent Ovarian Germ Cell Tumor
- Testicular Choriocarcinoma
- Testicular Embryonal Carcinoma
- Testicular Mixed Choriocarcinoma and Embryonal Carcinoma
- Testicular Mixed Choriocarcinoma and Yolk Sac Tumor
- Testicular Mixed Embryonal Carcinoma and Yolk Sac Tumor
- Testicular Yolk Sac Tumor

## Interventions

- **DRUG:** Carboplatin
- **BIOLOGICAL:** Filgrastim
- **DRUG:** Ifosfamide
- **OTHER:** Laboratory Biomarker Analysis
- **DRUG:** Paclitaxel

## Key facts

- **NCT ID:** NCT00467051
- **Lead sponsor:** Children's Oncology Group
- **Sponsor class:** NETWORK
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2007-11-05
- **Primary completion:** 2012-03-01
- **Final completion:** 2018-06-30
- **Target enrollment:** 20 (ACTUAL)
- **Last updated:** 2018-08-29

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00467051

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00467051, "Combination Chemotherapy in Treating Young Patients With Recurrent or Resistant Malignant Germ Cell Tumors". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT00467051. Licensed CC0.

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