# Efficacy and Safety of Activase (Ateplase) vs Placebo in Complicated Pleural Effusions (CPE)/Empyemas

> **NCT00468104** · NA · COMPLETED · sponsor: **Midwest Pulmonary and Critical Care** · enrollment: 100 (actual)

## Conditions studied

- Pleural Effusion Associated With Pulmonary Infection
- Bacterial Pleural Effusion Other Than Tuberculosis

## Interventions

- **DRUG:** Alteplase
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT00468104
- **Lead sponsor:** Midwest Pulmonary and Critical Care
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2004-04
- **Primary completion:** 2008-10
- **Final completion:** 2009-08
- **Target enrollment:** 100 (ACTUAL)
- **Last updated:** 2012-04-30

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00468104

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00468104, "Efficacy and Safety of Activase (Ateplase) vs Placebo in Complicated Pleural Effusions (CPE)/Empyemas". Retrieved via AI Analytics 2026-07-15 from https://api.ai-analytics.org/clinical/NCT00468104. Licensed CC0.

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