# Lapatinib in Combination With Radiation Therapy in Patients With Brain Metastases From HER2-Positive Breast Cancer

> **NCT00470847** · PHASE1 · COMPLETED · sponsor: **Nancy Lin, MD** · enrollment: 35 (actual)

## Conditions studied

- Breast Cancer
- Brain Metastases

## Interventions

- **DRUG:** Lapatinib
- **PROCEDURE:** Whole Brain Radiation
- **DRUG:** Herceptin

## Key facts

- **NCT ID:** NCT00470847
- **Lead sponsor:** Nancy Lin, MD
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2007-04
- **Primary completion:** 2009-12
- **Final completion:** 2012-06
- **Target enrollment:** 35 (ACTUAL)
- **Last updated:** 2014-05-22

## Collaborators

- [object Object]
- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00470847

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00470847, "Lapatinib in Combination With Radiation Therapy in Patients With Brain Metastases From HER2-Positive Breast Cancer". Retrieved via AI Analytics 2026-07-01 from https://api.ai-analytics.org/clinical/NCT00470847. Licensed CC0.

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