# Study in Patients With Advanced Non-Small Cell Lung Cancer Treated With Pemetrexed and Carboplatin Plus or Minus Sorafenib

> **NCT00473486** · PHASE1,PHASE2 · TERMINATED · sponsor: **University Hospital Muenster** · enrollment: 12 (actual)

## Conditions studied

- Carcinoma, Non-Small-Cell Lung

## Interventions

- **DRUG:** pemetrexed, carboplatin, sorafenib
- **DRUG:** pemetrexed, carboplatin, placebo

## Key facts

- **NCT ID:** NCT00473486
- **Lead sponsor:** University Hospital Muenster
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2007-05
- **Primary completion:** 2008-08
- **Final completion:** 2010-01
- **Target enrollment:** 12 (ACTUAL)
- **Why stopped:** Sorafenib administered in the combination with pemetrexed-carboplatin appears to enhance thrombocytopenia compared to historical data.
- **Last updated:** 2010-01-27

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00473486

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00473486, "Study in Patients With Advanced Non-Small Cell Lung Cancer Treated With Pemetrexed and Carboplatin Plus or Minus Sorafenib". Retrieved via AI Analytics 2026-08-11 from https://api.ai-analytics.org/clinical/NCT00473486. Licensed CC0.

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