# A Study of the Efficacy and Safety of Amitriptyline/Ketamine Topical Cream in Patients With Diabetic Peripheral Neuropathy

> **NCT00476151** · PHASE2 · COMPLETED · sponsor: **EpiCept Corporation** · enrollment: 226 (actual)

## Conditions studied

- Diabetic Peripheral Neuropathy
- Neuralgia

## Interventions

- **DRUG:** EpiCept NP-1 (4% Amitriptyline/ 2% Ketamine) Topical Cream
- **DRUG:** placebo cream

## Key facts

- **NCT ID:** NCT00476151
- **Lead sponsor:** EpiCept Corporation
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2007-07
- **Primary completion:** 2008-04
- **Final completion:** 2008-04
- **Target enrollment:** 226 (ACTUAL)
- **Last updated:** 2011-05-17


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00476151

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00476151, "A Study of the Efficacy and Safety of Amitriptyline/Ketamine Topical Cream in Patients With Diabetic Peripheral Neuropathy". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT00476151. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*