# Chemoprevention of Colorectal Adenomas

> **NCT00486512** · PHASE3 · TERMINATED · sponsor: **Colotech A/S** · enrollment: 350 (actual)

## Conditions studied

- Adenomatous Polyps

## Interventions

- **DRUG:** 0.5 mg calcitriol (1a -25-dihydroxycholecalciferol)
- **DRUG:** 75 mg acetylsalicylic acid (ASA) + 1250 mg calcium carbonate (CaCO3)
- **DRUG:** placebo to 0.5 mg calcitriol (1a -25-dihydroxycholecalciferol)
- **DRUG:** placebo to 75 mg acetylsalicylic acid (ASA) + 1250 mg calcium carbonate (CaCO3)
- **PROCEDURE:** Colonoscopy

## Key facts

- **NCT ID:** NCT00486512
- **Lead sponsor:** Colotech A/S
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2007-06
- **Primary completion:** 2010-11
- **Final completion:** 2010-11
- **Target enrollment:** 350 (ACTUAL)
- **Why stopped:** The overall program was terminated
- **Last updated:** 2020-09-03


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00486512

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00486512, "Chemoprevention of Colorectal Adenomas". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT00486512. Licensed CC0.

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