# Immunogenicity and Safety Study of Topical Recombinant Thrombin in Surgical Hemostasis

> **NCT00491608** · PHASE3 · COMPLETED · sponsor: **ZymoGenetics** · enrollment: 234 (actual)

## Conditions studied

- Spinal Surgery
- Vascular Surgery

## Interventions

- **BIOLOGICAL:** rThrombin

## Key facts

- **NCT ID:** NCT00491608
- **Lead sponsor:** ZymoGenetics
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2007-06
- **Primary completion:** 2008-07
- **Final completion:** 2008-07
- **Target enrollment:** 234 (ACTUAL)
- **Last updated:** 2012-01-13


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00491608

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00491608, "Immunogenicity and Safety Study of Topical Recombinant Thrombin in Surgical Hemostasis". Retrieved via AI Analytics 2026-07-25 from https://api.ai-analytics.org/clinical/NCT00491608. Licensed CC0.

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