# S0521, Combination Chemotherapy With or Without Gemtuzumab Followed By Tretinoin, Mercaptopurine, and Methotrexate or Observation in Treating Patients With Acute Promyelocytic Leukemia

> **NCT00492856** · PHASE3 · COMPLETED · sponsor: **SWOG Cancer Research Network** · enrollment: 105 (actual)

## Conditions studied

- Leukemia

## Interventions

- **DRUG:** mercaptopurine
- **DRUG:** methotrexate
- **DRUG:** tretinoin

## Key facts

- **NCT ID:** NCT00492856
- **Lead sponsor:** SWOG Cancer Research Network
- **Sponsor class:** NETWORK
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2007-06-01
- **Primary completion:** 2013-12-01
- **Final completion:** 2016-05-04
- **Target enrollment:** 105 (ACTUAL)
- **Last updated:** 2023-01-10

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00492856

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00492856, "S0521, Combination Chemotherapy With or Without Gemtuzumab Followed By Tretinoin, Mercaptopurine, and Methotrexate or Observation in Treating Patients With Acute Promyelocytic Leukemia". Retrieved via AI Analytics 2026-07-26 from https://api.ai-analytics.org/clinical/NCT00492856. Licensed CC0.

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