# Paclitaxel, Cisplatin, Gefitinib, and Radiation Therapy Followed by Surgery and Gefitinib in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction That Can Be Removed By Surgery

> **NCT00493025** · PHASE2 · TERMINATED · sponsor: **Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins** · enrollment: 19 (actual)

## Conditions studied

- Esophageal Cancer

## Interventions

- **DRUG:** cisplatin
- **DRUG:** gefitinib
- **DRUG:** paclitaxel
- **PROCEDURE:** adjuvant therapy
- **RADIATION:** radiation therapy

## Key facts

- **NCT ID:** NCT00493025
- **Lead sponsor:** Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2005-04
- **Primary completion:** 2013-03
- **Final completion:** 2013-03
- **Target enrollment:** 19 (ACTUAL)
- **Why stopped:** Closed due to early stopping rule-Low accrual
- **Last updated:** 2018-12-06

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00493025

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00493025, "Paclitaxel, Cisplatin, Gefitinib, and Radiation Therapy Followed by Surgery and Gefitinib in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction That Can Be Removed By Surgery". Retrieved via AI Analytics 2026-07-15 from https://api.ai-analytics.org/clinical/NCT00493025. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
