# Dose Dense Chemotherapy + Rituximab +/-Intensified High Dose Chemoimmunotherapy With Support of Peripheral Autologous Stem Cell in Diffuse Large B-Cell Lymphoma

> **NCT00499018** · PHASE3 · UNKNOWN · sponsor: **Fondazione Italiana Linfomi - ETS** · enrollment: 399 (estimated)

## Conditions studied

- Diffuse Large B-Cell Lymphoma
- IPI≥2

## Interventions

- **DRUG:** Rituximab
- **DRUG:** Ciclofosfamide
- **DRUG:** Doxorubicina
- **DRUG:** Vincristina
- **DRUG:** Prednisone
- **DRUG:** Pegfilgrastim
- **DRUG:** Mitoxantrone
- **DRUG:** ARA-C
- **DRUG:** Lenograstim
- **DRUG:** BCNU
- **DRUG:** ARA-C
- **DRUG:** VP-16
- **PROCEDURE:** ASCT
- **DRUG:** Ciclofosfamide
- **DRUG:** Doxorubicina
- **DRUG:** Vincristina

## Key facts

- **NCT ID:** NCT00499018
- **Lead sponsor:** Fondazione Italiana Linfomi - ETS
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2006-01
- **Primary completion:** 2011-06
- **Final completion:** 2013-09
- **Target enrollment:** 399 (ESTIMATED)
- **Last updated:** 2011-02-15

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00499018

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00499018, "Dose Dense Chemotherapy + Rituximab +/-Intensified High Dose Chemoimmunotherapy With Support of Peripheral Autologous Stem Cell in Diffuse Large B-Cell Lymphoma". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT00499018. Licensed CC0.

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