# Changes in Semen or Sperm Caused by Temozolomide in Patients With Newly Diagnosed, Progressive, or Recurrent Primary Malignant Brain Tumors

> **NCT00499798** · — · COMPLETED · sponsor: **Wake Forest University Health Sciences** · enrollment: 16 (actual)

## Conditions studied

- Brain and Central Nervous System Tumors
- Chemotherapeutic Agent Toxicity
- Infertility

## Interventions

_None listed._

## Key facts

- **NCT ID:** NCT00499798
- **Lead sponsor:** Wake Forest University Health Sciences
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** COMPLETED
- **Start date:** 2004-08
- **Primary completion:** 2009-06
- **Final completion:** 2014-09
- **Target enrollment:** 16 (ACTUAL)
- **Last updated:** 2017-05-30

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00499798

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00499798, "Changes in Semen or Sperm Caused by Temozolomide in Patients With Newly Diagnosed, Progressive, or Recurrent Primary Malignant Brain Tumors". Retrieved via AI Analytics 2026-05-29 from https://api.ai-analytics.org/clinical/NCT00499798. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*