# A Study to Assess the Cholesterol Lowering Effect of Ezetimibe/Simvastatin Combination Tablet Compared to Another Cholesterol Lowering Drug in Elderly Patients With High Cholesterol at High or Moderately High Risk for Coronary Heart Disease (0653A-128)

> **NCT00535405** · PHASE3 · COMPLETED · sponsor: **Organon and Co** · enrollment: 1289 (actual)

## Conditions studied

- Hypercholesterolemia

## Interventions

- **DRUG:** Atorvastatin 10 mg
- **DRUG:** Ezetimibe 10 mg/simvastatin 20 mg
- **DRUG:** Atorvastatin 20 mg
- **DRUG:** Ezetimibe 10 mg/simvastatin 40 mg
- **DRUG:** Atorvastatin 40 mg

## Key facts

- **NCT ID:** NCT00535405
- **Lead sponsor:** Organon and Co
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2007-11
- **Primary completion:** 2009-03
- **Final completion:** 2009-03
- **Target enrollment:** 1289 (ACTUAL)
- **Last updated:** 2024-05-16

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00535405

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00535405, "A Study to Assess the Cholesterol Lowering Effect of Ezetimibe/Simvastatin Combination Tablet Compared to Another Cholesterol Lowering Drug in Elderly Patients With High Cholesterol at High or Moderately High Risk for Coronary Heart Disease (0653A-128)". Retrieved via AI Analytics 2026-06-14 from https://api.ai-analytics.org/clinical/NCT00535405. Licensed CC0.

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