# A Randomized Controlled Study of Rolapitant for the Prevention of Nausea and Vomiting Following Surgery (Study P04937AM1)(COMPLETED)

> **NCT00539721** · PHASE2 · COMPLETED · sponsor: **Merck Sharp & Dohme LLC** · enrollment: 619 (actual)

## Conditions studied

- Postoperative Nausea and Vomiting

## Interventions

- **DRUG:** Rolapitant Dose 1
- **DRUG:** Rolapitant Dose 2
- **DRUG:** Rolapitant Dose 3
- **DRUG:** Rolapitant Dose 4
- **DRUG:** Ondansetron
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT00539721
- **Lead sponsor:** Merck Sharp & Dohme LLC
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2007-10
- **Primary completion:** 2008-07
- **Final completion:** 2008-07
- **Target enrollment:** 619 (ACTUAL)
- **Last updated:** 2013-11-01


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00539721

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00539721, "A Randomized Controlled Study of Rolapitant for the Prevention of Nausea and Vomiting Following Surgery (Study P04937AM1)(COMPLETED)". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT00539721. Licensed CC0.

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