# Analgesic Efficacy and Safety Study of Naproxcinod in Subjects With Osteoarthritis of the Knee

> **NCT00542555** · PHASE3 · COMPLETED · sponsor: **NicOx** · enrollment: 918 (actual)

## Conditions studied

- Osteoarthritis

## Interventions

- **DRUG:** Placebo
- **DRUG:** Naproxcinod 375 mg
- **DRUG:** Naproxen
- **DRUG:** Naproxcinod 750 mg

## Key facts

- **NCT ID:** NCT00542555
- **Lead sponsor:** NicOx
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2005-12
- **Primary completion:** —
- **Final completion:** 2007-09
- **Target enrollment:** 918 (ACTUAL)
- **Last updated:** 2011-06-17


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00542555

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00542555, "Analgesic Efficacy and Safety Study of Naproxcinod in Subjects With Osteoarthritis of the Knee". Retrieved via AI Analytics 2026-07-20 from https://api.ai-analytics.org/clinical/NCT00542555. Licensed CC0.

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