# Comparative Efficacy & Safety Study of Esomeprazole Versus Placebo for the Prevention of Gastric and Duodenal Ulcers With NSAID

> **NCT00542789** · PHASE3 · COMPLETED · sponsor: **AstraZeneca** · enrollment: 343 (actual)

## Conditions studied

- Gastric Ulcer
- Duodenal Ulcer
- Rheumatoid Arthritis
- Osteoarthritis
- Lumbago

## Interventions

- **DRUG:** Esomeprazole
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT00542789
- **Lead sponsor:** AstraZeneca
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2007-08
- **Primary completion:** —
- **Final completion:** 2009-02
- **Target enrollment:** 343 (ACTUAL)
- **Last updated:** 2010-05-28


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00542789

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00542789, "Comparative Efficacy & Safety Study of Esomeprazole Versus Placebo for the Prevention of Gastric and Duodenal Ulcers With NSAID". Retrieved via AI Analytics 2026-07-20 from https://api.ai-analytics.org/clinical/NCT00542789. Licensed CC0.

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