# Effects of Perioperative Nesiritide or Milrinone Infusion on Recovery From Fontan Surgery

> **NCT00543309** · PHASE2 · TERMINATED · sponsor: **John M Costello** · enrollment: 106 (actual)

## Conditions studied

- Heart Defects, Congenital

## Interventions

- **DRUG:** nesiritide
- **DRUG:** milrinone
- **DRUG:** placebo

## Key facts

- **NCT ID:** NCT00543309
- **Lead sponsor:** John M Costello
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2007-10
- **Primary completion:** 2013-01
- **Final completion:** 2013-07
- **Target enrollment:** 106 (ACTUAL)
- **Why stopped:** DSMB recommended termination based on interim outcomes analysis
- **Last updated:** 2018-06-25

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00543309

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00543309, "Effects of Perioperative Nesiritide or Milrinone Infusion on Recovery From Fontan Surgery". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT00543309. Licensed CC0.

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