# Study of Citicoline for the Treatment of Traumatic Brain Injury (COBRIT)

> **NCT00545662** · PHASE3 · TERMINATED · sponsor: **Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)** · enrollment: 1213 (actual)

## Conditions studied

- Traumatic Brain Injury

## Interventions

- **DRUG:** Placebo
- **DRUG:** citicoline

## Key facts

- **NCT ID:** NCT00545662
- **Lead sponsor:** Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- **Sponsor class:** NIH
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2007-07
- **Primary completion:** 2011-05
- **Final completion:** 2011-05
- **Target enrollment:** 1213 (ACTUAL)
- **Why stopped:** Trial stopped due to futility.
- **Last updated:** 2012-12-19


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00545662

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00545662, "Study of Citicoline for the Treatment of Traumatic Brain Injury (COBRIT)". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT00545662. Licensed CC0.

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