# Total Therapy Study XVI for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia

> **NCT00549848** · PHASE3 · COMPLETED · sponsor: **St. Jude Children's Research Hospital** · enrollment: 600 (actual)

## Conditions studied

- Acute Lymphoblastic Leukemia

## Interventions

- **DRUG:** Prednisone, Vincristine, Daunorubicin, PEG-L-asparaginase, Erwinia L-asparaginase, Doxorubicin, Cyclophosphamide, Cytarabine, Thioguanine
- **DRUG:** Clofarabine, Methotrexate, Mercaptopurine, Dexamethasone, Etoposide, Dasatinib

## Key facts

- **NCT ID:** NCT00549848
- **Lead sponsor:** St. Jude Children's Research Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2007-10-29
- **Primary completion:** 2020-09-26
- **Final completion:** 2022-03-26
- **Target enrollment:** 600 (ACTUAL)
- **Last updated:** 2022-08-23

## Collaborators

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- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00549848

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00549848, "Total Therapy Study XVI for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT00549848. Licensed CC0.

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