# Combination Chemotherapy, Autologous Stem Cell Transplant, and/or Radiation Therapy in Treating Young Patients With Extraocular Retinoblastoma

> **NCT00554788** · PHASE3 · COMPLETED · sponsor: **Children's Oncology Group** · enrollment: 60 (actual)

## Conditions studied

- Extraocular Retinoblastoma

## Interventions

- **PROCEDURE:** Autologous Bone Marrow Transplantation
- **PROCEDURE:** Autologous Hematopoietic Stem Cell Transplantation
- **DRUG:** Carboplatin
- **DRUG:** Cisplatin
- **DRUG:** Cyclophosphamide
- **DRUG:** Etoposide
- **BIOLOGICAL:** Filgrastim
- **PROCEDURE:** In Vitro-Treated Peripheral Blood Stem Cell Transplantation
- **RADIATION:** Radiation Therapy
- **DRUG:** Thiotepa
- **DRUG:** Vincristine Sulfate

## Key facts

- **NCT ID:** NCT00554788
- **Lead sponsor:** Children's Oncology Group
- **Sponsor class:** NETWORK
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2008-05-06
- **Primary completion:** 2018-06-30
- **Final completion:** 2024-12-31
- **Target enrollment:** 60 (ACTUAL)
- **Last updated:** 2025-01-13

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00554788

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00554788, "Combination Chemotherapy, Autologous Stem Cell Transplant, and/or Radiation Therapy in Treating Young Patients With Extraocular Retinoblastoma". Retrieved via AI Analytics 2026-07-20 from https://api.ai-analytics.org/clinical/NCT00554788. Licensed CC0.

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