# Extrapleural Pneumonectomy /Pleurectomy Decortication, IHOC Cisplatin and Gemcitabine With Amifostine and Sodium Thiosulfate Cytoprotection for Resectable Malignant Pleural Mesothelioma

> **NCT00571298** · PHASE1 · COMPLETED · sponsor: **Brigham and Women's Hospital** · enrollment: 141 (actual)

## Conditions studied

- Malignant Pleural Mesothelioma

## Interventions

- **PROCEDURE:** Extrapleural pneumonectomy (EPP)
- **DRUG:** Cisplatin
- **DRUG:** gemcitabine
- **DRUG:** amifostine
- **DRUG:** sodium thiosulfate
- **PROCEDURE:** Pleurectomy/Decortication

## Key facts

- **NCT ID:** NCT00571298
- **Lead sponsor:** Brigham and Women's Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2007-11
- **Primary completion:** 2011-11
- **Final completion:** 2015-06
- **Target enrollment:** 141 (ACTUAL)
- **Last updated:** 2017-01-23

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00571298

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00571298, "Extrapleural Pneumonectomy /Pleurectomy Decortication, IHOC Cisplatin and Gemcitabine With Amifostine and Sodium Thiosulfate Cytoprotection for Resectable Malignant Pleural Mesothelioma". Retrieved via AI Analytics 2026-07-19 from https://api.ai-analytics.org/clinical/NCT00571298. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*