# Triple III Comparison of Leflunomide Alone Versus Two DMARD Combinations in the Treatment of Rheumatoid Arthritis

> **NCT00579878** · PHASE3 · COMPLETED · sponsor: **University of Nebraska** · enrollment: 69 (actual)

## Conditions studied

- Rheumatoid Arthritis

## Interventions

- **DRUG:** Leflunomide
- **DRUG:** Methotrexate-Sulfasalazine-Hydroxychloroquine
- **DRUG:** Leflunomide-Sulfasalazine-Hydroxychloroquine

## Key facts

- **NCT ID:** NCT00579878
- **Lead sponsor:** University of Nebraska
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2001-03-27
- **Primary completion:** 2010-03-11
- **Final completion:** 2010-03-11
- **Target enrollment:** 69 (ACTUAL)
- **Last updated:** 2023-10-02


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00579878

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00579878, "Triple III Comparison of Leflunomide Alone Versus Two DMARD Combinations in the Treatment of Rheumatoid Arthritis". Retrieved via AI Analytics 2026-07-17 from https://api.ai-analytics.org/clinical/NCT00579878. Licensed CC0.

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