Acetaminophen in aSAH to Inhibit Lipid Peroxidation and Cerebral Vasospasm

Conditions

• Aneurysmal Subarachnoid Hemorrhage
• Cerebral Vasospasm

Interventions

• DRUG: Placebos for acetaminophen and N-acetylcysteine
• DRUG: APAP 1 gm every 6 hours and N-acetylcysteine placebo
• DRUG: NAC IV infusion at 0.5 gm hourly and APAP placebo
• DRUG: APAP 1 gm q6 hours, plus NAC IV infusion at 0.5 gm hourly
• DRUG: APAP 1.5 gm q6 hours, plus NAC IV infusion at 0.5 gm hourly

Sponsor

Vanderbilt University Medical Center

Collaborators

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