# Flexible Dose Titration Add-on Study to Treat Major Depressive Disorder

> **NCT00593879** · PHASE2 · COMPLETED · sponsor: **Targacept Inc.** · enrollment: 450 (actual)

## Conditions studied

- Major Depressive Disorder

## Interventions

- **DRUG:** Mecamylamine

## Key facts

- **NCT ID:** NCT00593879
- **Lead sponsor:** Targacept Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2005-02
- **Primary completion:** —
- **Final completion:** 2006-08
- **Target enrollment:** 450 (ACTUAL)
- **Last updated:** 2008-01-15


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00593879

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00593879, "Flexible Dose Titration Add-on Study to Treat Major Depressive Disorder". Retrieved via AI Analytics 2026-06-10 from https://api.ai-analytics.org/clinical/NCT00593879. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
