# Sirolimus, Tacrolimus and Short Course Methotrexate for Prevention of Acute GVHD in Recipients of Mismatched Unrelated Donor Allogeneic Stem Cell Transplantation

> **NCT00612274** · EARLY_PHASE1 · COMPLETED · sponsor: **Yale University** · enrollment: 26 (actual)

## Conditions studied

- Stem Cell Transplantation

## Interventions

- **DRUG:** tacrolimus
- **DRUG:** Sirolimus
- **DRUG:** Methotrexate

## Key facts

- **NCT ID:** NCT00612274
- **Lead sponsor:** Yale University
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2007-10
- **Primary completion:** 2014-10
- **Final completion:** 2014-10
- **Target enrollment:** 26 (ACTUAL)
- **Last updated:** 2016-11-30


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00612274

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00612274, "Sirolimus, Tacrolimus and Short Course Methotrexate for Prevention of Acute GVHD in Recipients of Mismatched Unrelated Donor Allogeneic Stem Cell Transplantation". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT00612274. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*