# Pharmacokinetic Drug Interaction Between Ezetimibe and Sirolimus After Single Dose Administration in Healthy Subjects

> **NCT00621101** · PHASE1 · COMPLETED · sponsor: **University Medicine Greifswald** · enrollment: 24 (actual)

## Conditions studied

- Pharmacokinetics
- Drug Interactions
- Hypercholesterolemia
- Immunosuppression

## Interventions

- **DRUG:** 1 tablet Ezetrol(R) (ezetimibe), MSD Sharp & Dohme GmbH, Germany
- **DRUG:** 1 tablet Rapamune(R) (sirolimus), Wyeth Pharma, Germany
- **DRUG:** 1 tablet Ezetrol(R) + 1 tablet Rapamune(R)

## Key facts

- **NCT ID:** NCT00621101
- **Lead sponsor:** University Medicine Greifswald
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2007-04
- **Primary completion:** 2007-06
- **Final completion:** 2007-06
- **Target enrollment:** 24 (ACTUAL)
- **Last updated:** 2008-02-22


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00621101

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00621101, "Pharmacokinetic Drug Interaction Between Ezetimibe and Sirolimus After Single Dose Administration in Healthy Subjects". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT00621101. Licensed CC0.

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