Allogeneic Hematopoietic Cell Transplantation for Severe Systemic Sclerosis

Conditions

• Systemic Scleroderma
• Severe Systemic Sclerosis

Interventions

• DRUG: fludarabine phosphate
• DRUG: Mycophenolic Acid
• DRUG: tacrolimus
• RADIATION: total-body irradiation
• PROCEDURE: bone marrow transplantation
• PROCEDURE: reduced intensity allogeneic hematopoietic stem cell transplantation
• PROCEDURE: quality-of-life assessment
• OTHER: laboratory biomarker analysis
• OTHER: flow cytometry
• PROCEDURE: biopsy

Sponsor

Fred Hutchinson Cancer Center

Collaborators

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