Phase I Study of Ixabepilone Plus Lapatinib With or Without Capecitabine in the Treatment of Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer
Stopped Slow Accrual
Conditions
- Locally Advanced or Metastatic Breast Cancer
Interventions
- DRUG: Ixabepilone, 32 mg/m^2 + Lapatinib, 1000 mg
- DRUG: Ixabepilone, 32 mg/m^2 + Lapatinib, 1250 mg
- DRUG: Ixabepilone, 40 mg/m^2 + Lapatinib, 1250 mg
- DRUG: Ixabepilone + Lapatinib + Capecitabine
Sponsor
R-Pharm
Collaborators