# EAGLE - Multicenter Study of the European Assessment Group for Lysis in the Eye

> **NCT00637468** · PHASE3 · TERMINATED · sponsor: **University Hospital Freiburg** · enrollment: 84 (actual)

## Conditions studied

- Retinal Artery Occlusion
- Fibrinolysis
- Visual Acuity
- Stroke
- Hemodilution

## Interventions

- **DRUG:** Intravenous injection of heparin
- **DRUG:** Intravenous injection of acetazolamide
- **PROCEDURE:** Local intra-arterial fibrinolysis
- **PROCEDURE:** Globe massage
- **DRUG:** Topical use of beta-blocker
- **DRUG:** Isovolaemic haemodilution
- **DRUG:** Acetylsalicylic acid

## Key facts

- **NCT ID:** NCT00637468
- **Lead sponsor:** University Hospital Freiburg
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2002-09
- **Primary completion:** —
- **Final completion:** —
- **Target enrollment:** 84 (ACTUAL)
- **Why stopped:** Due to results of conditional power analysis performed at the first interim analysis and due to observed spectrum of adverse events.
- **Last updated:** 2008-03-18

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00637468

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00637468, "EAGLE - Multicenter Study of the European Assessment Group for Lysis in the Eye". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT00637468. Licensed CC0.

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