# A Study of Mifepristone vs. Placebo in the Treatment of Patients With Major Depression With Psychotic Features

> **NCT00637494** · PHASE3 · TERMINATED · sponsor: **Corcept Therapeutics** · enrollment: 292 (actual)

## Conditions studied

- Psychotic Depression
- Severe Major Depression With Psychotic Features
- Psychosis

## Interventions

- **DRUG:** mifepristone
- **DRUG:** placebo

## Key facts

- **NCT ID:** NCT00637494
- **Lead sponsor:** Corcept Therapeutics
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2008-03
- **Primary completion:** 2014-06
- **Final completion:** 2014-06
- **Target enrollment:** 292 (ACTUAL)
- **Why stopped:** DRC recommended stopping study as it had missed its primary endpoint
- **Last updated:** 2017-06-05


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00637494

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00637494, "A Study of Mifepristone vs. Placebo in the Treatment of Patients With Major Depression With Psychotic Features". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT00637494. Licensed CC0.

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