# Pharmacokinetics of Rifabutin Combined With Antiretroviral Therapy in Patients With TB/HIV Co-infection in South Africa

> **NCT00640887** · PHASE2 · COMPLETED · sponsor: **French National Agency for Research on AIDS and Viral Hepatitis** · enrollment: 48 (estimated)

## Conditions studied

- HIV Infections
- Tuberculosis

## Interventions

- **DRUG:** rifabutin in combination with efavirenz
- **DRUG:** rifabutin in combination with nevirapine
- **DRUG:** rifabutin in combination with lopinavir/ritonavir

## Key facts

- **NCT ID:** NCT00640887
- **Lead sponsor:** French National Agency for Research on AIDS and Viral Hepatitis
- **Sponsor class:** OTHER_GOV
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2009-02
- **Primary completion:** 2010-10
- **Final completion:** 2010-10
- **Target enrollment:** 48 (ESTIMATED)
- **Last updated:** 2011-06-20


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00640887

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00640887, "Pharmacokinetics of Rifabutin Combined With Antiretroviral Therapy in Patients With TB/HIV Co-infection in South Africa". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT00640887. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
