# Effects of Cognitive Behavioral Therapy on Brain Serotonin Activity in People With Depression

> **NCT00641108** · PHASE2,PHASE3 · COMPLETED · sponsor: **University of Pennsylvania** · enrollment: 30 (actual)

## Conditions studied

- Depression

## Interventions

- **DRUG:** ADAM SPECT plus Cognitive Therapy
- **DRUG:** ADAM SPECT plus No Therapy

## Key facts

- **NCT ID:** NCT00641108
- **Lead sponsor:** University of Pennsylvania
- **Sponsor class:** OTHER
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2008-01
- **Primary completion:** 2011-12
- **Final completion:** 2011-12
- **Target enrollment:** 30 (ACTUAL)
- **Last updated:** 2020-04-16

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00641108

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00641108, "Effects of Cognitive Behavioral Therapy on Brain Serotonin Activity in People With Depression". Retrieved via AI Analytics 2026-06-10 from https://api.ai-analytics.org/clinical/NCT00641108. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*