# Safety and Efficacy Study of Isolagen TherapyTM in the Treatment of Nasolabial Fold Wrinkles

> **NCT00649428** · PHASE3 · COMPLETED · sponsor: **Castle Creek Biosciences, LLC.** · enrollment: 203 (actual)

## Conditions studied

- Bilateral Nasolabial Fold Wrinkles

## Interventions

- **BIOLOGICAL:** Autologous Human Fibroblast (azficel-T)
- **BIOLOGICAL:** Placebo

## Key facts

- **NCT ID:** NCT00649428
- **Lead sponsor:** Castle Creek Biosciences, LLC.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2006-10
- **Primary completion:** 2008-07
- **Final completion:** 2009-05
- **Target enrollment:** 203 (ACTUAL)
- **Last updated:** 2012-03-13


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00649428

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00649428, "Safety and Efficacy Study of Isolagen TherapyTM in the Treatment of Nasolabial Fold Wrinkles". Retrieved via AI Analytics 2026-06-05 from https://api.ai-analytics.org/clinical/NCT00649428. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*