# Efficacy and Safety of Valdecoxib and Naproxen in Treating the Signs and Symptoms of Rheumatoid Arthritis (RA) in a Severe Rheumatoid Arthritis Patients

> **NCT00650455** · PHASE4 · COMPLETED · sponsor: **Pfizer** · enrollment: 489 (actual)

## Conditions studied

- Arthritis, Rheumatoid

## Interventions

- **DRUG:** valdecoxib
- **DRUG:** naproxen
- **DRUG:** placebo

## Key facts

- **NCT ID:** NCT00650455
- **Lead sponsor:** Pfizer
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2003-02
- **Primary completion:** 2005-01
- **Final completion:** 2005-01
- **Target enrollment:** 489 (ACTUAL)
- **Last updated:** 2008-07-21


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00650455

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00650455, "Efficacy and Safety of Valdecoxib and Naproxen in Treating the Signs and Symptoms of Rheumatoid Arthritis (RA) in a Severe Rheumatoid Arthritis Patients". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT00650455. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*