Aflibercept, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed or Recurrent Glioblastoma Multiforme, Gliosarcoma, or Other Malignant Glioma

NCT00650923 · clinicaltrials.gov ↗

PHASE1

Phase

COMPLETED

Status

61

Enrollment

NIH

Sponsor class

Conditions

Adult Anaplastic Astrocytoma
Adult Anaplastic Oligodendroglioma
Adult Giant Cell Glioblastoma
Adult Glioblastoma
Adult Gliosarcoma
Adult Mixed Glioma
Recurrent Adult Brain Tumor

Interventions

DRUG: ziv-aflibercept
PROCEDURE: radiation therapy
DRUG: temozolomide
PROCEDURE: pharmacological study
PROCEDURE: laboratory biomarker analysis

Sponsor

National Cancer Institute (NCI)