# Double-Blind, Double Dummy, Randomized Comparison Study to Evaluate the Efficacy and Safety of Valdecoxib 10 mg Once Daily and Naproxen 500 mg Twice Daily in Treating the Signs and Symptoms of Osteoarthritis of the Knee

> **NCT00652808** · PHASE3 · COMPLETED · sponsor: **Pfizer** · enrollment: 265 (actual)

## Conditions studied

- Osteoarthritis
- Knee

## Interventions

- **DRUG:** valdecoxib
- **DRUG:** naproxen

## Key facts

- **NCT ID:** NCT00652808
- **Lead sponsor:** Pfizer
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2004-05
- **Primary completion:** —
- **Final completion:** 2004-09
- **Target enrollment:** 265 (ACTUAL)
- **Last updated:** 2008-04-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT00652808

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT00652808, "Double-Blind, Double Dummy, Randomized Comparison Study to Evaluate the Efficacy and Safety of Valdecoxib 10 mg Once Daily and Naproxen 500 mg Twice Daily in Treating the Signs and Symptoms of Osteoarthritis of the Knee". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT00652808. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*